Inspired by U.S. President John F. Kennedy's Alliance for Progress, the Colorado Chapter of Partners of the Americas (COPoA) is an international development 501(c)3 nonprofit and nonpartisan organization based in Denver and Greeley, Colorado, founded in 1964. Colorado made history as the first U.S.-Brazil partnership, with the former Minas Gerais Chapter.

In 2017, COPoA adopted a hybrid working model, welcoming members worldwide. The Colorado Chapter has a history of educational and cultural exchanges, including programs in the environment, dance, music, English teaching, and youth. Since 2020, the chapter has collaborated with Partners chapters, student chapters, and affiliate organizations in Argentina, Colombia, Bolivia, Brazil, Ecuador, Guatemala, Honduras, Peru, and the U.S.

Colorado's goals include expanding these activities across the Americas and strengthening civic engagement, education, language acquisition, leadership development, and social entrepreneurship.